The Maryland Institute for Technology in the Humanities (MITH), working in cooperation with the Office of Digital Humanities at the NEH and the National Library of Medicine at the NIH, hosted the Shared Horizons symposium in April 2013. The symposium explored collaboration, research methodologies, and the interpretation of evidence arising from the interdisciplinary opportunities in this burgeoning area of biomedical-driven humanities scholarship. There were opportunities for disciplinary cross-fertilization through a mix of formal and informal presentations, which promoted a rich exchange of ideas about how large-scale quantitative methods can lead to new understandings of human culture. Bringing together researchers from the digital humanities and bioinformatics communities, the symposium explored ways in which these two communities might fruitfully collaborate on projects that bridge the humanities and medicine. The symposium was supported by a Digital Humanities Cooperative Agreement with additional support from Research Councils UK (HC-50015-12).